Fig. 4From: Metabolic responses of plasma to extreme environments in overwintering Tibetan frogs Nanorana parkeri: a metabolome integrated analysisPathway analysis of differential metabolites in plasma from summer- and winter-collected N. parkeri in positive ion mode (a) and negative ion mode (b). The -ln(P value) represents the enrichment score. The impact score (0–1) indicates the pathway topological importance of the metabolites. The color and size of each circle is based on P values and pathway impact values, respectivelyBack to article page