| Winter | Summer | Two-way ANOVA | ||||
---|---|---|---|---|---|---|---|
W + 3 | W + 1 | S + 3 | S + 1 | Season | Age | Interaction | |
LIVER | |||||||
sirt1 | 2.53 ± 0.24 | 3.22 ± 0.21 | 1.02 ± 0.08 | 1.52 ± 0.11 | < 0.001 | 0.002 | 0.597 |
sirt2 | 4.15 ± 0.33 | 6.20 ± 0.46 | 5.21 ± 0.27 | 6.99 ± 0.27 | 0.012 | < 0.001 | 0.697 |
sirt3 | 1.54 ± 0.16 | 1.60 ± 0.12 | 0.81 ± 0.04 | 0.82 ± 0.04 | < 0.001 | 0.762 | 0.799 |
sirt4 | 0.59 ± 0.06 | 0.64 ± 0.07 | 0.34 ± 0.02 | 0.48 ± 0.03 | < 0.001 | 0.081 | 0.406 |
sirt5 | 6.86 ± 0.54 | 10.3 ± 0.52 | 5.47 ± 0.21 | 6.83 ± 0.26 | < 0.001 | < 0.001 | 0.014 |
sirt6 | 0.69 ± 0.08 | 0.72 ± 0.05 | 0.42 ± 0.03 | 0.51 ± 0.05 | 0.001 | 0.531 | 0.935 |
sirt7 | 1.07 ± 0.08 | 1.17 ± 0.07 | 1.11 ± 0.06 | 1.20 ± 0.04 | 0.177 | 0.385 | 0.795 |
pgc1α | 3.29 ± 0.90 | 5.03 ± 0.63 | 4.14 ± 0.33 | 4.75 ± 0.32 | 0.633 | 0.058 | 0.350 |
cpt1a | 20.1 ± 3.21 | 28.7 ± 2.37 | 3.94 ± 0.48 | 8.57 ± 0.98 | < 0.001 | 0.004 | 0.357 |
cs | 30.1 ± 1.95 | 27.9 ± 1.18 | 16.3 ± 1.84 | 19.9 ± 1.32 | < 0.001 | 0.666 | 0.077 |
ucp1 | 261.4 ± 16.1 | 496.2 ± 44.8 | 603.2 ± 45.9 | 1228.3 ± 105.9 | < 0.001 | < 0.001 | 0.003 |
WSM | |||||||
sirt1 | 3.90 ± 0.30 | 1.78 ± 0.17 | 1.04 ± 0.09 | 0.77 ± 0.05 | < 0.001 | < 0.001 | < 0.001 |
sirt2 | 3.23 ± 0.27 | 2.10 ± 0.14 | 3.44 ± 0.39 | 1.96 ± 0.08 | 0.884 | < 0.001 | 0.488 |
sirt3 | 0.65 ± 0.06 | 0.58 ± 0.06 | 0.35 ± 0.06 | 0.22 ± 0.01 | < 0.001 | 0.081 | 0.548 |
sirt4 | 0.60 ± 0.06 | 0.31 ± 0.03 | 0.39 ± 0.04 | 0.29 ± 0.03 | 0.017 | < 0.001 | 0.044 |
sirt5 | 12.9 ± 1.37 | 5.19 ± 0.43 | 5.48 ± 1.02 | 2.72 ± 0.31 | < 0.001 | < 0.001 | 0.011 |
sirt6 | 0.55 ± 0.03 | 0.31 ± 0.03 | 0.32 ± 0.03 | 0.18 ± 0.02 | < 0.001 | < 0.001 | 0.092 |
sirt7 | 1.77 ± 0.16 | 1.00 ± 0.07 | 0.71 ± 0.04 | 0.43 ± 0.03 | < 0.001 | < 0.001 | 0.014 |
pgc1α | 6.32 ± 0.83 | 4.40 ± 0.80 | 2.82 ± 0.27 | 2.55 ± 0.25 | 0.002 | 0.050 | 0.500 |
cpt1a | 71.6 ± 8.58 | 49.2 ± 5.78 | 4.69 ± 0.48 | 9.78 ± 1.17 | < 0.001 | 0.112 | 0.020 |
cs | 235.2 ± 19.4 | 152.0 ± 12.8 | 63.9 ± 3.11 | 64.9 ± 4.01 | < 0.001 | 0.002 | 0.006 |
ucp3 | 173.0 ± 33.1 | 165.1 ± 10.8 | 25.1 ± 1.74 | 46.1 ± 2.38 | < 0.001 | 0.794 | 0.498 |