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Fig. 7 | Frontiers in Zoology

Fig. 7

From: Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across seasons and advancing age in gilthead sea bream (Sparus aurata)

Fig. 7

Seasonal local DNA methylation and correlation with sirt1 gene expression in muscle of one-year-old fish. a Site-specific DNA methylation (%) of sirt1 in white skeletal muscle (WSM) of one-year-old fish in winter (black bars) and summer (gray bars). Data are the mean ± SEM of 8–10 fish. CpG position with a circle indicates significant differences between seasons by t-test (P < 0.05). b Correlation between mean DNA methylation of SP1-related CpG sites (CpG2, 3) in the sirt1 gene promoter region and sirt1 gene expression in white skeletal muscle (WSM) of one-year-old fish. Red and green points represent data from winter and summer, respectively

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Frontiers in Zoology

ISSN: 1742-9994