Figure 7

Tertiary structures of tick salivary lectins. Panel A displays five predicted tertiary structures ryncolin1 from snake venom (UniProt: D8VNS7) and four tick lectins, IxoderinA, IxoderinB, DorinM, OMFREP (respective UniProt: I6LAP5, Q5IUW6, Q7YXM0 and Q8MUC2). The tertiary structures depict the conserved disulfide bridges (indicated by roman numerals), loops, β-sheets that forms the β-hairpin, and the α-helix. All structures are colored from the N-terminus (blue) to the C-terminus (red). Below each tertiary structure is the respective electrostatic potential in 180° turns (blue = positive; red = negative; white = neutral). A tertiary structural alignment in Panel B depicts the Cα protein backbone (color codes for each structure is presented on the right).