Fig. 3
From: Remarkable metabolic reorganization and altered metabolic requirements in frog metamorphic climax
Reorganization of lipid metabolism in the liver during metamorphic climax. a–b Free fatty acids (FAAs) and acylcarnitines varied (p < 0.05, one-way ANOVA) during natural metamorphosis. Different letters denote significant differences between groups (p < 0.05), as shown by the Student–Newman–Keuls post hoc test after one-way ANOVA. c FFAs and acylcarnitines differed in content between control and T3-treated groups. Each box represents a mean ± SE; *, p < 0.05. d Transcriptional changes of genes involved in lipid metabolism in the liver after T3-treatment; a positive log-transformed fold change value means upregulation in T3-treated group, and vice versa; *, p < 0.05. e Histological sections of the liver. Triacylglycerol (TAG) is the major form of hepatic fat storage in the liver and accounts for the red color in Oil Red O (ORO) staining. f Network presenting the adjustments on lipid metabolism in the liver. Metabolic fluxes are presented as arrows between items. Items and arrows with blue, red, cyan, and black colors indicate downregulated/decreased, upregulated/increased, unchanged, and undetected, respectively; and similarly hereinafter