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Fig. 5 | Frontiers in Zoology

Fig. 5

From: Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across seasons and advancing age in gilthead sea bream (Sparus aurata)

Fig. 5

Age and seasonal changes in DNA methylation of sirt1 in gilthead sea bream liver. Site-specific DNA methylation (%) of sirt1 in the liver in winter (a) and summer (b) of fish of different ages (+ 3, three-year-old; + 1, one-year-old). Data are the mean ± SEM of 8–10 fish. CpG position with a circle indicates significant differences between ages by t-test (P < 0.05). Dashed lines indicate the mean methylation of all individuals and positions

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