Fig. 4From: Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across seasons and advancing age in gilthead sea bream (Sparus aurata)Age and seasonal changes in DNA methylation of gilthead sea bream sirt3. Site-specific DNA methylation (%) of sirt3 in liver (a, b) and white skeletal muscle (WSM) (c, d) of fish of different ages (+ 3, three-year-old; + 1, one-year-old) in winter and summer. Data are the mean ± SEM of 8–10 fish. CpG position with a circle indicates significant differences between ages by t-test (P < 0.05). Dashed lines indicate the mean methylation of all individuals and positionsBack to article page