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Fig. 2 | Frontiers in Zoology

Fig. 2

From: A nemertean excitatory peptide/CCHamide regulates ciliary swimming in the larvae of Lineus longissimus

Fig. 2

Analysis of EP/CCHamide receptors. a Phylogenetic analysis of protostome EP/CCHamide receptors and related deuterostome receptors. Color coding according to the phylogenetic group as depicted in the simplified tree on the upper right corner. SH-like support values are shown for the indicated nodes. Scale bar on the lower right corner shows amino acid substitution rate per site. The endothelin 1 receptor branch was shortened to half its size (indicated by the two crossing lines). Asterisk highlights the L. longissimus receptor that was biochemically characterized. b Activation of the L. longissimus EP receptor by the two L. longissimus excitatory peptides EP1 (EC50 = 78 nmol/l) and EP2 (EC50 = 59 nmol/l)

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