Table 4 Over-represented families of paralogous genes based on the wFleaBase annotations. In total 3,978 families encompassed 24,102 genes (genes per family: median — 3, 5–95 % interval — 2–18)

UP

Omcl36

Pupal cuticle protein

59

11

9

UP

Omcl49

Pupal cuticle protein

47

6

7

UP

Omcl195

Zinc-metalloproteinase

19

9

8

UP

Omcl240

Globin

15

4

5

UP

Omcl335

Vitellogenin/Superoxide dismutase

12

6

6

UP

Omcl886

Cuticle protein

5

3

ns

UP

Omcl2139

Unknown

2

2

2

UP

Omcl3428

Cyclin a

2

2

ns

UP

Omcl3680

Unknown

2

2

2

DN

Omcl23

Neurexin/Complement C1q

82

5

5

DN

Omcl277

Elongation of very long chain fatty acids protein

15

3

4

DN

Omcl329

C-type lectin

12

6

5

DN

Omcl1532

Unknown

3

2

3

DN

Omcl1713

Unknown

3

2

ns

DN

Omcl1963

Unknown

3

3

3

DN

Omcl2758

Unknown

2

2

2

DN

Omcl3591

Unknown

2

2

2