Table 1 Schedule of retinotectal development in different anurans
| Â | E. coqui | D. pictus | P. pustulosus 1 | X. laevis 2 |
|---|---|---|---|---|
NeuroD expression (Fig. 1: blue asterisks) | Â | Â | Â | Â |
Onset of NeuroD expression in retina | TS 5 | ? | ? | NF 23 |
NeuroD expression downregulated in central retina | TS 9 | ? | ? | NF 35–36 |
Retinotectal differentiation (Fig. 1: blue triangles) | Â | Â | Â | Â |
Optic vesicle | TS 3+ | GH 18 | ≤GH24 | NF 21–226 |
Tectofugal fibers | TS 5 | GH 22 | ? | ? |
Optic vesicle forms cup | TS 5 | GH 22 | ≤GH24 | NF 26–276 |
Lens forms | TS 5 | GH 22 | ≤GH24 | NF 326 |
Retinofugal fibers grow out | TS 6 | GH 22 | GH 22 | NF 29–306 |
First cells differentiate in retina (PCNA -) | TS 6 | GH 23 | ≤GH24 | NF 28–296,7 |
Retinofugal fibers in optic chiasm | TS 7 | GH 23 | GH 23 | NF 326 |
Retinofugal fibers reach contralateral tectum | TS 7 | GH 23 | ? | NF 35–376 |
Inner plexiform layer in retina | TS 9 | GH 27 | GH 27 | NF 35–376 |
First cells differentiate in tectum (PCNA-) | TS 9 | GH 27 | GH 24 | NF 41–459,10 |
Outer plexiform layer in retina | TS 11 | GH 30 | Go 27 | NF 36–386 |
Tectal layers 7–9 | TS 11 | Go 28 | Go 27 | NF 4811 |
Tectal layer 5 | TS 13 | Go 28 | Go 27 | NF 4811 |
Retinal layer of outer segments of photoreceptors | TS 12 | Go 28 | Go 27 | NF 438 |
First ipsilateral retinofugal fibers | TS 9 | Go 30 | ? | NF 54–5512 |
Neuropils in contralateral thalamus | TS 13 | Go 30 | ? | NF 35–3613 |
Tectal layers 1–43 | TS 15+6 | Go 42 | Go 41 | NF 519 |
Retinofugal fibers cover contralat. tectum completely3 | TS 15+12 | Go 45 | ? | NF 668 |
Retinal growth4 (Fig. 1: red circles) | Â | Â | Â | Â |
40 % | TS 8 | Go 28 | Go 28–41 | ? |
60 % | TS 9 | Go 29–30 | Go 28–41 | ? |
75 % | TS 10 | Go 30–31 | Go 28–41 | ? |
90 % | TS 11+ | Go 37 | Go 28–41 | ? |
Tectal growth4 (Fig. 1: green circles) | Â | Â | Â | Â |
40 % | TS 8 | Go 29/ | Go 28–41 | ? |
60 % | TS 9 | Go 29–30 | Go 28–41 | ? |
75 % | TS11 | Go 30–31 | Go 28–41 | ? |
90 % | TS 13- | Go 31 | Go 28–41 | ? |