Alignment and phylogenetic analysis of the myc oncogene. (A) The partial protein sequence of myc from P. dumerilii (AM697687) was aligned with corresponding sequences from S. purpuratus (NP_999744), D. melanogaster (Q9W4S7), C. elegans (NP_001022773), human c-myc (P01106), and human n-myc (1202343A). The human myc-like protein (NP_001028253) was used as out-group. Red color indicates 70% consensus and blue color 40% consensus. (B) A Bayesian protein tree generated using the aligned protein sequences revealed that Platynereis myc shows highest relation to human c-myc. Posterior probabilities are plotted at the nodes. The scale bar represents the substitutions per site according to the model of amino acid evolution applied.