Schematic illustration of an adhesive organ in controls and in macif1 dsRNA treated animals. Anchor cell (blue), adhesive (red) and releasing gland (green) within the epidermis (white). Five morphological alterations are obvious. 1) The microvilli core of macif1 dsRNA treated animals is closed in controls, whereas it appears open in treated animals. 2) The microvilli are shorter and 3) miss the dense core of actin filaments. 4) The treated animals lack intermediate filaments in the cytoplasm of anchor cells and 5) a reduced cytoplasmic interaction with hemidesmosomes is present.